Should you microdose cannabis for menopause?

Menopause disrupts your body's hormonal balance. This can cause sleep disturbances, anxiety, mood swings, muscle aches, and a reduced quality of life. Microdosing cannabis offers natural relief for these symptoms without causing psychoactive effects that interfere with daily life.

Research shows that menopause disrupts the endocannabinoid system (ECS), which regulates mood, sleep, pain, and hormone function. Cannabis microdoses help rebalance this system and provide relief for menopausal symptoms. A 2022 survey of perimenopausal and postmenopausal women found that nearly 79% of cannabis users applied it to menopause symptoms. Sleep disturbance was the most common reason for use (67%), followed by mood and anxiety issues (46%).

Our THC edibles contain precise microdoses starting at 2 mg THC per serving, which gives you control over symptom relief. These low-dose formulations provide therapeutic benefits without impairment, so you can manage menopause while staying sharp and functional throughout your day.

Menopause and cannabis: The science

Menopause is more than the end of menstruation. Your body produces dramatically less estrogen and progesterone, which affects every system from sleep cycles to pain sensitivity. These hormonal changes impact your endocannabinoid system (ECS), the network responsible for mood, sleep, appetite, and stress responses.

According to research, the ECS interacts with sex hormones throughout your reproductive years. When estrogen and progesterone levels decline during menopause, ECS activity changes significantly. This disruption contributes to many symptoms women experience, including depression, anxiety, mood swings, decreased libido, and sleep difficulties.

Cannabis compounds work with your existing ECS receptors to restore balance. THC and CBD don't replace hormones, but they support the systems that regulate mood, comfort, and sleep quality.

Cannabis provides targeted relief for menopause symptoms

Cannabis can provide relief for women who are experiencing issues caused by menopausal hormone changes. The most common reasons for cannabis use in menopausal women are sleep issues, anxiety, mood swings, as well as muscle and joint aches.

Sleep disruption and night sweats

Cannabis addresses sleep problems through multiple mechanisms. THC helps you fall asleep faster by reducing the time to sleep onset, while CBD maintains deeper sleep cycles and reduces nighttime awakening. Unlike prescription sleep medications that create artificial drowsiness, cannabis supports your body's natural sleep processes. 

Sleep Plus gummies contain 2 mg THC, 25 mg CBD, and 3 mg melatonin for comprehensive sleep support that won't leave you groggy the next morning.

Mood swings and anxiety

Estrogen decline affects neurotransmitter balance, leading to irritability, anxiety, and mood instability. CBD has demonstrated anti-anxiety properties, while low-dose THC can improve mood without causing euphoria or impairment.

Cannabis microdoses help regulate emotional responses without masking your personality or cognitive function. Many women report feeling more emotionally balanced during stressful situations and better able to handle daily challenges.

Joint pain and muscle aches

Estrogen has anti-inflammatory properties, so declining levels increase inflammation throughout your body. This leads to joint stiffness, muscle aches, and general discomfort that wasn't present before menopause.

Cannabis reduces inflammation at the cellular level through CB2 receptors found in immune tissues. Both THC and CBD have demonstrated anti-inflammatory effects, with studies showing reduced inflammatory markers, like TNF-α and IL-6, after cannabis use.

Our Relax Plus gummies provide 5 mg THC and 25 mg CBD per serving, offering anti-inflammatory benefits with mild relaxation that doesn't interfere with daytime activities.

Microdosing prevents cannabis side effects in menopause

A comprehensive 2023 analysis of 1,485 menopausal women, 74% indicated that cannabis was helpful for their symptoms. The most common reasons for use were sleep (65%), anxiety (45%), and muscle/joint aches (33%). 

Cannabis has a biphasic effect, meaning low and high doses produce opposite results. Low doses reduce anxiety and promote relaxation, while higher doses can increase anxiety and paranoia.

Microdosing typically involves 2–5 mg of THC combined with equal or higher amounts of CBD. These therapeutic doses provide symptom relief without psychoactive effects that interfere with work, relationships, or daily responsibilities.

Cannabis consumption methods for menopausal women

Research shows that 84% of surveyed women smoke cannabis, 78% use edibles, and 53% use vaping oils. However, smoking and vaping irritate airways and may worsen hot flashes or respiratory symptoms common during menopause.

Edibles offer the most precise dosing and longest-lasting effects, typically 4–8 hours of symptom relief. Cannabis beverages work faster than hard edibles but still avoid the respiratory irritation of inhaled methods.

Buzz Drops contain 2.5 mg THC and 2.5 mg CBD per dropper, so you can add precise microdoses to any beverage without taste or calories.

How to microdose cannabis for menopause relief

Start with the lowest possible THC dose (2 mg) combined with a higher CBD dose (5–25 mg) to maximize therapeutic benefits while minimizing psychoactive effects. Take your dose at the same time each day for consistent symptom management.

Matching cannabis products to menopause symptoms

Different cannabinoid ratios target different symptom clusters:

• Sleep and night sweats: Higher CBD ratios with 2–3 mg THC promote restful sleep without morning grogginess. Sleep Plus gummies include melatonin for comprehensive sleep support.
• Anxiety and mood swings: Balanced 1:1 or 2:1 CBD:THC ratios provide emotional stability. Bliss gummies contain 5 mg each of THC and CBD for gentle mood support.
• Pain and inflammation: Higher CBD doses (25 mg) with low THC (2–5 mg) target inflammatory pain. Relax Plus gummies provide anti-inflammatory benefits with mild relaxation.
• Energy and focus: Very low THC doses (2.5 mg) with supportive nutrients combat menopause-related fatigue. Energy gummies combine cannabis with B12 and L-theanine for sustained mental clarity.

Advanced strategies for menopause cannabis use

Once you establish your baseline dosing, these techniques optimize cannabis use for long-term menopause management:

• Symptom tracking: Record doses alongside symptom severity to identify patterns and optimal timing. Many women find their needs change throughout the week or month.
• Product rotation: Use different products for different situations. Keep Buzz Packs for social situations, sleep gummies for bedtime, and daytime formulas for work days.
• Cycle with hormone changes: Some women find their cannabis needs fluctuate with remaining hormonal cycles during perimenopause. Adjust doses based on when symptoms typically worsen.
• Stack with other wellness practices: Cannabis works synergistically with exercise, meditation, and good nutrition. It's not a replacement for healthy lifestyle habits but enhances their effectiveness.

The goal isn't to feel "high" but to restore the balance menopause has disrupted. Our microdosed products provide targeted relief that fits into your existing routines without compromising your professional or personal life.

Shop our THC collection and discover how cannabis microdosing can help you navigate menopause with greater comfort and confidence.

Resources

Dahlgren, M. Kathryn PhD1,2,3; El-Abboud, Celine BA1,2; Lambros, Ashley M. BS1,2; Sagar, Kelly A. PhD1,2,3; Smith, Rosemary T. BS1,2; Gruber, Staci A. PhD1,2,3. A survey of medical cannabis use during perimenopause and postmenopause. Menopause 29(9):p 1028-1036, September 2022. | DOI: 10.1097/GME.0000000000002018

Santoro A, Mele E, Marino M, Viggiano A, Nori SL, Meccariello R. The Complex Interplay between Endocannabinoid System and the Estrogen System in Central Nervous System and Periphery. Int J Mol Sci. 2021 Jan 19;22(2):972. doi: 10.3390/ijms22020972. PMID: 33478092; PMCID: PMC7835826.

Babyn K, Ross S, Makowsky M, Kiang T, Yuksel N. Cannabis use for menopause in women aged 35 and over: a cross-sectional survey on usage patterns and perceptions in Alberta, Canada. BMJ Open. 2023 Jun 21;13(6):e069197. doi: 10.1136/bmjopen-2022-069197. PMID: 37344107; PMCID: PMC10314536.

Further reading

What are the best CBD gummies for menopause?

Microdosing THC for pain relief

Is it safe to drive while microdosing THC?

Microdosing THC for sleep

What are the best sleep gummies for adults?

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