What are the best CBD gummies for quitting smoking?

May 14, 2025The nama Team

Gummies with cannabidiol (CBD) reduce nicotine cravings and ease withdrawal symptoms when quitting smoking. Their microdosed formula works with your endocannabinoid system (ECS) to regulate mood, stress, and addiction responses. 

One peer-reviewed study found that CBD reverses the smoker's attention bias toward tobacco cues and decreases the perceived pleasantness of cigarette images.

We've selected the best CBD gummies that address different aspects of nicotine dependence. All our products undergo rigorous third-party lab testing to verify potency and purity. We use all-natural ingredients and avoid artificial additives or fillers that might compromise your health goals.

What are the best CBD gummies for quitting smoking?

Looking for a better way to kick the habit? Try nama's collection of CBD gummies and get precise cannabinoid amounts in tasty, convenient treats. Our vegan, lab-tested gummies give you relief when cravings strike.

Euphoria sour gummies: Best for breaking the nicotine reward cycle

Our Euphoria sour gummies deliver 10 mg THC and 10 mg CBD per piece. This balanced ratio disrupts nicotine's hold on your brain's reward system. The full-spectrum formula contains a range of beneficial compounds from the hemp plant, while the sour berry flavor provides a satisfying sensory experience that helps replace the oral fixation of smoking. 

If you’re not a fan of sour, maybe our strawberry-infused Euphoria edibles will satisfy your cravings.

Bliss gummies: When you need daytime relaxation

For those who need to remain clear-headed throughout the day, our Bliss gummies offer a more subtle approach with 5 mg THC and 5 mg CBD per piece. The melon flavor provides a refreshing alternative to the taste of cigarettes. The taste also comes in handy during the morning hours when tobacco cravings are strongest.

Relax Plus Gummies: Best for stress-triggered smokers

If stress and anxiety trigger your smoking habit, our Relax Plus gummies combine a THC microdose with 25 mg CBD to deal with jitters. The fresh watermelon flavor delivers a pleasant taste experience while the cannabinoid profile targets smoking-related anxiety. 

Pain Plus gummies: A comprehensive formulation for full-body relief

For smokers dealing with multiple withdrawal symptoms, our Pain Plus gummies contain a comprehensive cannabinoid profile: THC, CBC, CBD, CBG, and CBN per each delicious edible. This full-spectrum formula addresses physical discomfort while helping normalize brain chemistry disrupted by nicotine dependence.

Sleep Plus gummies: Soothe those night cravings

Evening cravings and sleep disruption frequently sabotage quitting attempts. Our Sleep Plus gummies restore healthy sleep patterns while reducing nighttime urges to smoke. Combining 2 mg THC, 25 mg CBD, and 3 mg melatonin, these gummies help you maintain the restful sleep you need when you try to end your nicotine dependence. 

How does CBD help me quit smoking?

Research shows that CBD targets the brain mechanisms that make quitting so difficult, without the side effects of cessation aids.

Cigarettes lose their appeal

CBD modulates the endocannabinoid system, which regulates reward and reinforcement pathways in the brain. It also normalizes depleted anandamide levels to reduce the rewarding properties of cigarettes. Anandamide is the neurotransmitter most frequently disrupted by nicotine addiction. In a 2013 clinical study, smokers using CBD inhalers cut their cigarette use by 40% in just one week, while the control group showed no reduction. 

CBD disrupts attention to smoking triggers

Your brain pays special attention to smoking cues: the sight of someone with a cigarette, the smell of tobacco smoke, or tobacco use on TV can trigger cravings. A 2018 study discovered that CBD "reversed attentional bias to cigarette cues," making smoking triggers invisible to the addiction centers in your brain. 

CBD eliminates physical withdrawal symptoms

The physical symptoms of nicotine withdrawal (e.g., irritability, restlessness, anxiety, and difficulty concentrating) lead smokers back to cigarettes. Smith, et. al. demonstrated that CBD treatment eliminated these symptoms in nicotine-dependent subjects. CBD's effectiveness matched FDA-approved cessation medications such as Chantix and Wellbutrin, but without their concerning side effects. 

Smith's team noted this effect was consistent across different CBD doses (7.5 mg, 15 mg, and 30 mg), which means even lower doses are effective. Many people are just discovering the benefits of microdosing cannabis, which also provides therapeutic relief for anxiety, pain, inflammation, and sleep disturbances without intoxication or impairing side effects.

CBD prevents withdrawal-induced pain sensitivity

Nicotine withdrawal increases sensitivity to pain. CBD prevents this heightened pain response during early and prolonged abstinence. This effect stems from CBD's proven anti-inflammatory properties and its ability to modulate vanilloid receptors in the nervous system, which play a key role in pain perception. 

Your body processes nicotine differently with CBD

CBD changes how your body processes nicotine. Smith's research found that CBD reduced blood cotinine levels (a nicotine metabolite) by 27% without affecting nicotine levels. This metabolic shift contributes to CBD's ability to reduce withdrawal intensity and could decrease nicotine reinforcement over time. CBD also influences the cytochrome P450 enzyme system that metabolizes nicotine to slow the conversion process that perpetuates addiction.

CBD relieves withdrawal-related anxiety

Anxiety is the most challenging withdrawal symptom for quitters. Hindocha's research explains how CBD's anti-anxiety properties target this obstacle. It achieves this by activating serotonin receptors, enhancing GABA signaling (the brain's primary inhibitory neurotransmitter), and reducing activity in the amygdala, the brain's fear center. CBD reduces withdrawal-related anxiety without sedation or other side effects, so you can manage stress without reaching for cigarettes. 

CBD rebalances the brain's reward system

Nicotine hijacks your body's ECS and disrupts your mood, stress, and reward pathways. By balancing anandamide levels, your brain chemistry returns to its pre-addiction state. CBD accomplishes this by inhibiting FAAH, the enzyme that breaks down anandamide, so this natural mood enhancer builds up in the brain. 

Our low-dose CBD gummies are a convenient, precisely dosed delivery method for managing smoking withdrawal symptoms throughout the day. Choose broad-spectrum CBD options that deliver a mix of beneficial cannabinoids without THC if you’re concerned about drug testing. 

Our full-spectrum gummies offer superior relief because combined cannabis compounds trigger the entourage effect. Trace amounts of THC work synergistically with CBD and other cannabinoids to enhance each other’s effectiveness, which is why they are valuable for smokers dealing with multiple withdrawal symptoms.

How much CBD should I take to quit smoking?

The amount of CBD you need to quit smoking depends on your withdrawal symptoms and body weight. According to a 2024 study:

  • 40–100 mg of oral CBD decreases your craving for nicotine.
  • A 30 mg CBD dose reduces anxiety behaviors during nicotine withdrawal.
  • A 60 mg CBD dose relieves somatic withdrawal symptoms such as irritability and restlessness.
  • Even the lowest dose tested (15 mg) was effective.

If you’ve never consumed CBD before, start with a morning microdose (5–10 mg), then take a second dose when cravings typically peak. If you notice limited effects after three days, increase by 5–10 mg per dose. For those who enjoy the full-spectrum relief combined with THC, make sure you keep the THC levels ultra low (1–2 mg) to avoid unwanted psychoactive effects while still benefiting from the entourage effect.

Consistency matters more than quantity. Daily use maintains steady cannabinoid levels in your system. Many successful quitters find better results taking CBD before cravings appear rather than responding to them.

How long does CBD take to work?

Smoked cannabis hits your system almost instantly, giving you that quick relief from cravings. The downside is that the effects fade just as fast, usually within 1–3 hours. Besides, smoking isn't exactly a healthier alternative when trying to kick a cigarette habit.

CBD gummies take a bit longer to kick in, usually 30–120 minutes, but they provide a much smoother experience. Instead of that sharp spike and crash, you get steady relief that lasts 4–6 hours. This means you're protected through multiple craving cycles without constantly redosing.

For best results, take your gummies about 30 minutes before situations that typically make you reach for a smoke. This way, CBD is active exactly when you need it most.

Are CBD gummies safe?

CBD gummies are well-tolerated with an impressive safety profile. Even high doses of CBD (up to 600 mg) have been shown to cause minimal adverse side effects. As a non-psychoactive compound derived from organic hemp, CBD is a natural alternative for those seeking a smoke-free life.

Potential side effects of CB include:

  • Dry mouth.
  • Drowsiness.
  • Temporary drop in blood pressure.
  • Changes in appetite.
  • Digestive discomfort.
  • Headache.
  • Interactions with certain medications.

These side effects are most likely to appear if you're new to cannabis products, have a low tolerance, take higher-than-recommended doses, or combine CBD with certain medications. 

Product QUIZ

Need help deciding what product is best for you? Take our quiz, just three questions until your perfect match!

Best CBD gummies for quitting smoking FAQ

CBD and nicotine operate completely differently in your body. Nicotine hijacks your brain's reward pathways, creating powerful addiction with harmful health consequences. CBD naturally regulates your stress response without addictive properties, which makes it superior for relief from irritability and feelings of anxiety during withdrawal.

Full-spectrum CBD products deliver a range of beneficial compounds that tackle multiple withdrawal symptoms simultaneously. While nicotine replacement therapies simply maintain your dependence in a different form, CBD helps break the addiction cycle completely. 

1000 mg of CBD as a single dose would be excessive for smoking cessation. Beneficial results are achieved at much lower doses, typically around 30 mg per serving. Most reputable brands offer different potency options for appropriate per-serving consumption. When you see "1000 mg" on product packaging, this refers to the total bottle content, not what you should take at once.

If you’re trying to quit smoking, start with 15–20 mg doses, especially if you're new to CBD. High-potency options are economical for regular users but require precise dosing with your product's dropper or pre-measured gummies. Always consult a healthcare professional before experimenting with high doses to stay safe.

Smoking any substance, including weed or CBD flower, can irritate your lungs. Smoking something else when quitting cigarettes is somewhat counterproductive. CBD gummies and tinctures offer the therapeutic effects of cannabinoids without respiratory risks. 

Nicotine-free vapes might seem tempting, but even these can harm your lungs. Since quality standards for vape production vary, edible CBD products are the safest, most consistent option.

Standard drug tests typically screen for THC metabolites, not CBD itself. Pure CBD isolate products shouldn't trigger a positive result. Full-spectrum CBD contains trace amounts of THC (under 0.3%), which could potentially accumulate in your system with regular use of high doses. 

If you’re concerned about drug testing, choose broad-spectrum CBD products that offer many of the same benefits through additional hemp compounds without THC. Verify product safety through third-party lab reports from reputable brands to confirm THC content matches what's on the label.

Flavors can transform how ex-smokers experience CBD. nama's flavor options satisfy oral fixation while replacing tobacco taste with pleasant alternatives. Our triple berry gummies with THC and other delicious fruit varieties are praised in our customer reviews for their authentic profiles. Unlike the medicinal taste of conventional cessation products, our gummies create an enjoyable experience that becomes part of new daily habits. 

CBD works well alongside conventional smoking cessation methods. Many users successfully combine CBD with nicotine patches for a comprehensive approach to quitting. CBD helps manage the psychological aspects of withdrawal, while the patch addresses physical nicotine dependence. This combination often results in better nicotine reduction than either method alone. 

Unlike some dietary supplement interactions, CBD generally doesn't interfere with Quitine Nicotine Gum or similar products. Since CBD affects nicotine metabolism, you may need lower doses of conventional products when used together. Always discuss your plant-based approach to quitting with your healthcare professional for personalized advice.

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Resources

Hindocha C, Freeman TP, Grabski M, Stroud JB, Crudgington H, Davies AC, Das RK, Lawn W, Morgan CJA, Curran HV. Cannabidiol reverses attentional bias to cigarette cues in a human experimental model of tobacco withdrawal. Addiction. 2018 May 1;113(9):1696–705. doi: 10.1111/add.14243. Epub ahead of print. PMID: 29714034; PMCID: PMC6099309.

Celia J.A. Morgan, Ravi K. Das, Alyssa Joye, H. Valerie Curran, Sunjeev K. Kamboj,

Cannabidiol reduces cigarette consumption in tobacco smokers: Preliminary findings,

Addictive Behaviors, Volume 38, Issue 9, 2013, Pages 2433-2436, ISSN 0306-4603,

https://doi.org/10.1016/j.addbeh.2013.03.011.

Smith LC, Tieu L, Suhandynata RT, Boomhower B, Hoffman M, Sepulveda Y, Carrette LLG, Momper JD, Fitzgerald RL, Hanham K, Dowling J, Kallupi M, George O. Cannabidiol reduces withdrawal symptoms in nicotine-dependent rats. Psychopharmacology (Berl). 2021 Aug;238(8):2201-2211. doi: 10.1007/s00213-021-05845-4. Epub 2021 Apr 28. PMID: 33909102; PMCID: PMC8295227.

Samantha N. Cheeks, Belle Buzzi, Ashley Valdez, Allison S. Mogul, M. Imad Damaj, Christie D. Fowler, Cannabidiol as a potential cessation therapeutic: Effects on intravenous nicotine self-administration and withdrawal symptoms in mice, Neuropharmacology, Volume 246, 2024,

109833, ISSN 0028-3908, https://doi.org/10.1016/j.neuropharm.2023.109833.

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